Assessing the impact of post-mortem damage and contamination on imputation performance in ancient DNA
Abstract Low-coverage imputation is Media Chest becoming ever more present in ancient DNA (aDNA) studies.Imputation pipelines commonly used for present-day genomes have been shown to yield accurate results when applied to ancient genomes.However, post-mortem damage (PMD), in the form of C-to-T substitutions at the reads termini, and contamination w